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As it has euphoric results alike to other opioids, oxycodone one of the drugs misuse in the current opioid epidemic in the United States. An abuse-deterrent mixture with naloxone is present in direct-release tablets. If inserted, the naloxone precipitates opioid withdrawal features and blocks the result of the medication. However, there have been concerns raised about the success of the abuse prevention measures. Oxycodone Powder Online.